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Growth Hormone and the Effects on Alzheimer’s Disease

Human growth hormone or HGH is naturally produced by pituitary gland to stimulate cell and tissue growth. Besides its effects on muscle, bone, and cartilage, HGH also affects any other cells throughout the body and helps protect them from aging and degeneration. 

In this article, we will focus on the effects of HGH on Alzheimer’s disease – one of the most common degenerative diseases.

What is Alzheimer’s disease?

Alzheimer’s disease is the most common type of dementia generally found in people over the age of 65. It causes memory loss, as well as thinking and behavior problems. The damage of brain and nerve cells in Alzheimer’s has been thought to be related to the accumulation of plaques and tangles within the brain.

The symptoms of Alzheimer’s become worsen over time. In late stage, patients may lose major cognitive functions and the ability to live their normal daily lives. The current treatments of Alzheimer’s are able to slow – but not to stop – the progression of the disease. Hence, it’s significant to find more effective approaches to treat or delay the development of Alzheimer’s.

Does HGH benefit people with Alzheimer’s?

The effect of HGH is possibly associated with Alzheimer’s development, as there’s evidence that the levels of HGH is reduced in patients with Alzheimer’s disease. 

Lately, some studies on mice have reported that IGF-1 – a hormone released from the liver and HGH target tissues as a result of HGH stimulation – can reduce beta-amyloid, which is a form of plaque that can accumulate within the brain. Since HGH is crucial for IGF-1 production, and, moreover, has the proven benefits on anti-aging, it can be a promising agent for Alzheimer’s drug development. Yet, in human, the results of HGH treatment in patients with Alzheimer’s are still contentious. 

However, long-term HGH therapy does have some indirect benefits for patients with Alzheimer’s, including improved mood and cognitive function, resulting in better psychological well-being and better quality of life. 

HGH supplement

The condition of growth hormone deficiency can impact on most tissues and organs. Therefore, the replacement of HGH is significant to restore the normal body functions.

The injection of HGH can generally treat these following:

  • Growth hormone deficiency (GHD) in adults and children
  • Prader-Willi syndrome
  • Turner syndrome
  • Small for gestational age and idiopathic short stature in children
  • Muscle wasting disease


GENOTROPIN is a prescription synthetic recombinant HGH (rHGH) used for the treatment of GHD for over 30 years. 

The portable option, Pfizer GENOTROPIN 36 IU GoQuick Pen, is the product of Pfizer in form of disposable pre-filled pen that is easy to learn how to use.

However, GENOTROPIN is an underprescription drug that may cause some adverse effects – including muscle pain, hypertension, and hypothyroidism. So, you should consult your doctor and follow the instruction carefully.

  • Ghigo E, Nicolosi M, Arvat E, Marcone A, Danelon F, Mucci M, Franceschi M, Smirne S, Camanni F., Growth hormone secretion in Alzheimer’s disease: studies with growth hormone-releasing hormone alone and combined with pyridostigmine or arginine. Dementia. 1993 Nov-Dec;4(6):315-20.
  • Michela Leboffe Tabaku, Human Growth Hormones: What are the Benefits?, National Center for Health Research
  • St.Paul, Minn., Does Growth Hormone Drug Slow Alzheimer’s Disease?, American Academy of Neurology, November 2008
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