Human growth hormone or HGH is a natural hormone secreted by the pituitary gland. The important functions of HGH involve growth, cell regeneration, and tissue building, that’s why its levels rise during childhood and peak during puberty. In adults, HGH levels decline, yet it still exerts some crucial effects as the following:
Increased muscle mass and physical strength
HGH stimulates cell regeneration and collagen synthesis, resulting in increased muscle mass and strength. In healthy individuals, HGH also helps increase muscle responsiveness and exercise performance.
Increased bone strength
Secreted HGH consequently induces the release of IGF-1, whose function is to regulate the balance of bone formation and resorption. HGH-IGF1 axis stimulates bone reforming and prevents bone density loss, decreasing risk of osteoporosis.
Promoted injury recovery
HGH stimulates the production of protein, new cells, and connective tissues to rapidly heal wounds and tears. Also, in cases of bone fracture, HGH increases the proliferation of new bone cells and cartilage cells, thus boosting rebuilding process.
Enhanced fat and weight loss
HGH can accelerate fat breakdown, while inhibiting fat mass build-up, leading to lower blood lipid levels, decreased body fat, and gradual loss of weight.
Decreased risk of cardiovascular disease
The risk of cardiovascular disease is induced by altered lipoprotein metabolism, and increased body fat. As HGH stimulates lipolysis and reduces fat mass, it likewise reduces risk of cardiovascular disease.
Improved mood and cognitive function
The adequate release of HGH is related to better cognitive function, and psychological well-being. According to the result of one study, adults who were growth hormone deficient had improved mood and cognitive function after 6-month of growth hormone therapy.
Improved the severity of chronic kidney disease
In CKD patients, HGH shows to relieve inflammation and malnutrition, which are common complications of the disease, thus improving morbidity and mortality rate.
Alleviated PCOS symptoms
Polycystic ovary syndrome or PCOS is a sex hormone-associated disease that quite common in women of reproductive age. HGH helps maintain the balance of sex hormone, meanwhile, reduced PCOS symptoms and complications, such as depression, anxiety, and insulin resistance.
How to boost HGH levels
Doing more exercise, lessen sugar intake, and taking arginine or GABA supplements are some practical ways to boost HGH release. However, in people with growth hormone deficiency, these approaches may not be enough to restore the adequate levels of HGH.
Recently, the standard treatment for growth hormone deficiency involves the injection of recombinant HGH (rHGH) to replace growth hormone in the body. The indications of using rHGH injection include:
- Adults and children who have growth hormone deficiency
- Patients with Prader-Willi syndrome and Turner syndrome
- Children with Small gestational age (SGA) and Idiopathic short stature (ISS)
GENOTROPIN is a synthetic recombinant HGH product used for the replacement of growth hormone in both children and adults. It is launched by Pfizer, and has been approved by FDA as an effective treatment for growth hormone deficiency and other related diseases for many years.
Pfizer GENOTROPIN 36 IU GoQuick Pen, is an easy-to-use and portable product that you can purchase in Thailand. However, GENOTROPIN is a prescription product, so if interested, please consult your doctor and follow the instructions carefully.
- Gunawardane K, Krarup Hansen T, Sandahl Christiansen J, et al. Normal Physiology of Growth Hormone in Adults. [Updated 2015 Nov 12]. In: Feingold KR, Anawalt B, Boyce A, et al., editors. Endotext [Internet]. South Dartmouth (MA): MDText.com, Inc.; 2000-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK279056/
- Joe Boland, 9 Benefits of Human Growth Hormone, Including More Muscle & Less Fat (https://draxe.com/nutrition/supplements/human-growth-hormone/), June 2017